References
This web page was produced as an assignment for Gen677 at UW-Madison Spring 2009

Michishita, E., McCord, R.A., Berber, E., Kioi, M., Padilla-Nash, H., Damian, M., Cheung, P., Kusumoto, R., Kawahara, T.L., Barrett, J.C., et al.  (2008).  SIRT6 is a histone h3 lysine9 deacetylase that modulates telomeric chromatin.  Nature 452, 492-496. doi:10.1038/nature06736

Mostoslavsky, R., Chua, K.F., Lombard, D.B., Pang, W.W., Fischer, M.R., Gellon, L., Liu, P., Mostoslavsky, G., Franco, S., Murphy, M.M., et al.  (2006).  Genomic instability and aging like phenotype in the absence of mammalian SIRT6.  Cell 124, 315-329. doi:10.1016/j.cell.2005.11.044   

Kawahara, T.L., Michishita, E., Adler, A.S., Damian, Mara., Berber, E., Lin, Meihong., McCord, R.A., Ongaigui, K.C., Boxer, L.D., Chang, H.Y., Chua, K.F. (2008).  SIRT6 links histone H3 lysine 9 deacetylation to NF-kB-dependent gene expression and organismal life span.  Cell 136, 62-74. doi: 10.1016/j.cell.2008.10.052

Mayor, S. (2009).  Unraveling the secrets of aging.  BMJ 338, 3024.  doi:10.1136/bmj.a3024

Conger, Krista. (2009).  Stanford researchers uncover link between two aging pathways.  Stanford StoryBank.  Retrieved from http://storybank.stanford.edu/stories/stanford-researchers-uncover-link-between-two-aging-pathways
Sauve A.A., Celic I., Avalos J., Deng H., Boeke J.D., Schramm V.L.  (2001).  Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions.  Biochemistry 40:15456-15463 doi: 10.1021/bi011858j

Dutnail, R.N., Pillus, L.  (2001).  Deciphering NAD-Dependent Deacetylases.  Cell 105, 161-164. doi:10.1016/S0092-8674(01)00305-1

North BJ, Verdin E (2004). "Sirtuins: Sir2-related NAD-dependent protein deacetylases". Genome Biol. 5 (5): 224. doi:10.1186/gb-2004-5-5-224. PMID 15128440. 


Mark Devries
Email [email protected]
last updated 1/22/09
http://www.gen677.weebly.com