This web page was produced as an assignment for Gen677 at UW-Madison Spring 2009
Figure 1. These are the IPs showing that SIRT6 associates with the RELA subunit of NF-kB
Picture A/B shows that only SIRT6 strongly associates with RELA, which is seen by the strong band and a weak interaction with SIRT7. But also notice in picture B that SIRT1 is able to be pulled down with RELA after a longer time
Picture D/E are demonstrating that both endogenous SIRT6/RELA are able to interact with GST tagged SIRT6/RELA
Mark Devries
Email [email protected]
last updated 1/22/09
http://www.gen677.weebly.com
